Diphenylether

Diphenylether

SCHEMBL11580362

CCCCCCCCCCCCc1ccccc1.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.59
KCNH2 Q12809 1/20 0.59
PPARG P37231 2/20 0.53
PPARA Q07869 2/20 0.53
SIGMAR1 Q99720 2/20 0.51
HTR2A P28223 2/20 0.51
ESR1 P03372 2/20 0.50
ADRA2A P08913 2/20 0.50
ADORA3 P0DMS8 2/20 0.50
TACR2 P21452 2/20 0.50
SLC6A2 P23975 2/20 0.50
SLC6A4 P31645 2/20 0.50
SLC6A3 Q01959 2/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
LMNA P02545 1/20 0.50
SHBG P04278 1/20 0.50
TP53 P04637 1/20 0.50
CYP3A4 P08684 1/20 0.50
HSPD1 P10809 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylether SCHEMBL27770101 0.98 LTA4H (0.58) LTA4HKCNH2PPARGPPARASIGMAR1
SCHEMBL4546800 0.94 LTA4H (0.62) LTA4HKCNH2HTR2AESR1ADRA2A
SCHEMBL12721515 0.94 LTA4H (0.62) LTA4HKCNH2HTR2AESR1ADRA2A
SCHEMBL12056748 0.94 LTA4H (0.62) LTA4HKCNH2HTR2AESR1ADRA2A
SCHEMBL16558294 0.94 LTA4H (0.62) LTA4HKCNH2HTR2AESR1ADRA2A
SCHEMBL15312061 0.94 LTA4H (0.62) LTA4HKCNH2HTR2AESR1ADRA2A
SCHEMBL2453789 0.93 LTA4H (0.61) LTA4HKCNH2HTR2AESR1ADRA2A
SCHEMBL10630392 0.93 LTA4H (0.61) LTA4HKCNH2HTR2AESR1ADRA2A
SCHEMBL5667215 0.92 LTA4H (0.65) LTA4HKCNH2HTR2AESR1ADRA2A
SCHEMBL23085167 0.90 PPARA (0.62) LTA4HPPARGPPARACETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105461848-A SiO2 coated polyacrylate hybrid emulsion and preparation method as well as application thereof UNIV SOUTH CHINA TECH 2016-04-06 CN claimed
CN-105418820-A Hydroxyl-containing styrene-acrylate copolymer/SiO2 hybrid emulsion, preparation method and application thereof UNIV SOUTH CHINA TECH 2016-03-23 CN claimed
CN-105367702-A Polyacrylate/nano SiO2 hybrid emulsion with high coating film hardness and tolerance and preparation method for polyacrylate/nano SiO2 hybrid emulsion and application of polyacrylate/nano SiO2 hybrid emulsion UNIV SOUTH CHINA TECH 2016-03-02 CN claimed
CN-105461848-A SiO2 coated polyacrylate hybrid emulsion and preparation method as well as application thereof UNIV SOUTH CHINA TECH 2016-04-06 CN disclosed
CN-105418820-A Hydroxyl-containing styrene-acrylate copolymer/SiO2 hybrid emulsion, preparation method and application thereof UNIV SOUTH CHINA TECH 2016-03-23 CN disclosed
CN-105367702-A Polyacrylate/nano SiO2 hybrid emulsion with high coating film hardness and tolerance and preparation method for polyacrylate/nano SiO2 hybrid emulsion and application of polyacrylate/nano SiO2 hybrid emulsion UNIV SOUTH CHINA TECH 2016-03-02 CN disclosed
US-4074967-A Dyestuff preparations for dyeing and printing natural and synthetic polyamide fibre materials HOECHST AKTIENGESELLSCHAFT (DT) 1978-02-21 US disclosed