SCHEMBL1158063

SCHEMBL1158063

CSCC[C@H](NC(=O)CN)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.51
FNTA P49354 4/20 0.51
FNTB P49356 4/20 0.51
PGGT1B P53609 1/20 0.51
CA2 P00918 2/20 0.49
MAPK1 P28482 2/20 0.49
CA1 P00915 1/20 0.49
ALDH1A1 P00352 2/20 0.48
USP2 O75604 1/20 0.48
TP53 P04637 1/20 0.48
ALOX15 P16050 1/20 0.48
NPSR1 Q6W5P4 2/20 0.48
FOLH1 Q04609 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30051670 1.00 LMNA (0.51) LMNAFNTAFNTBPGGT1BCA2
SCHEMBL1158062 1.00 LMNA (0.51) LMNAFNTAFNTBPGGT1BCA2
SCHEMBL30052673 0.94 FNTA (0.50) LMNAFNTAFNTBPGGT1BCA2
Trifluoroacetic Acid SCHEMBL8763021 0.91 SMN1; SMN2 (0.47) LMNAFNTAFNTBPGGT1BCA2
SCHEMBL11662923 0.89 FNTA (0.49) LMNAFNTAFNTBPGGT1BCA2
SCHEMBL11662915 0.89 FNTA (0.49) LMNAFNTAFNTBPGGT1BCA2
SCHEMBL30440147 0.88 FNTA (0.55) FNTAFNTBPGGT1B
SCHEMBL30051202 0.88 FNTA (0.45) LMNAFNTAFNTBPGGT1BCA2
SCHEMBL7987401 0.88 FNTA (0.48) LMNAFNTAFNTBPGGT1BCA2
SCHEMBL7987408 0.88 FNTA (0.48) LMNAFNTAFNTBPGGT1BCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 266 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12534510-B2 Peptide-receptive MHC-I complex compositions and methods THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-01-27 US claimed
EP-3817757-B1 PEPTIDE DEFICIENT-MHC CLASS I/CHAPERONE COMPOSITIONS AND METHODS UNIV CALIFORNIA (US) 2026-01-07 EP claimed
EP-4136098-B1 PEPTIDE-RECEPTIVE MHC-I COMPLEX COMPOSITIONS AND METHODS FOR THEIR GENERATION UNIV CALIFORNIA (US) 2025-12-17 EP claimed
US-20240307428-A1 SYNERGISTIC COMPOSITION FOR MAINTENANCE OF HEALTHY BALANCE OF MICROFLORA KIMBERLY-CLARK WORLDWIDE, INC. (US) 2024-09-19 US claimed
US-20240294601-A1 PEPTIDE DEFICIENT-MHC CLASS I/CHAPERONE COMPOSITIONS AND METHODS THE REGENTS OF THE UNIVERSITY OF CALIFORNA 2024-09-05 US claimed
US-12029748-B2 Synergistic composition for maintenance of healthy balance of microflora KIMBERLY-CLARK WORLDWIDE, INC. (US) 2024-07-09 US claimed
US-11814420-B2 Peptide deficient-MHC class I/chaperone compositions and methods THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-11-14 US claimed
CN-115776987-A Barcoded exchangeable peptide-MHC multimer libraries 瑞佩尔托利免疫医药股份有限公司 2023-03-10 CN claimed
EP-4136098-A1 PEPTIDE-RECEPTIVE MHC-I COMPLEX COMPOSITIONS AND METHODS The Regents of the University of California (US) 2023-02-22 EP claimed
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-12-08 US claimed
US-6472201-B1 GROWING AND TESTING MICROORGANISMS IN A MULTITEST FORMAT WHICH UTILIZES A GEL FORMING MATRIX FOR THE RAPID SCREENING OF CLINICAL AND ENVIRONMENTAL CULTURES BIOLOG, INC. 2002-10-29 US claimed
JP-2000508335-A 2000-07-04 JP claimed
EP-0934270-A1 A METHOD OF TREATING CANCER Merck & Co., Inc. (US) 1999-08-11 EP claimed
WO-1997045412-A1 A METHOD OF TREATING CANCER MERCK & CO., INC. (US) 1997-12-04 WO claimed
EP-0783517-A2 THIOL-FREE INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE MERCK & CO. INC. (US) 1997-07-16 EP claimed
EP-0226304-B1 COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC SANKYO COMPANY LIMITED (JP) 1991-08-28 EP claimed
US-4757066-A Reduces renal toxicity SANKYO COMPANY LIMITED (JP) 1988-07-12 US claimed
EP-0226304-A1 Composition containing a penem or carbapenem antibiotic SANKYO COMPANY LIMITED (JP) 1987-06-24 EP claimed
US-4095000-A AMINO ACIDS AND DERIVATIVES, POLYHYDROXY COMPOUNDS, NUTRIENTS, HYDROLYSIS Brenner, Max (CH) 1978-06-13 US claimed
US-3959519-A Fortification of food materials with a methionine source E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-05-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS VIP, DNPEP, PEPD LMNA 3184/4885FNTA 776/4885FNTB 452/4885
US-12534510-B2 Peptide-receptive MHC-I complex compositions and methods MICA, TAP2, TAP1 LMNA 3263/4885FNTA 2320/4885FNTB 375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.