Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.59 |
| ▸ | PTPRC | P08575 | 1/20 | 0.50 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | FGR | P09769 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.42 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2302266 | 0.95 | ADORA2A (0.61) | ADORA2APTPRCKCNA3BRD4MAPT | |
| SCHEMBL10546429 | 0.90 | ADORA2A (0.58) | ADORA2AKCNA3BRD4MAPTPOLB | |
| SCHEMBL10583717 | 0.87 | ADORA2A (0.55) | ADORA2AKCNA3BRD4MAPTPOLB | |
| SCHEMBL11580693 | 0.87 | CCNE2 (0.52) | ADORA2APTPRCMAPTPOLBKMT2A | |
| SCHEMBL11579860 | 0.87 | ADORA2A (0.54) | ADORA2APTPRCKCNA3BRD4MAPT | |
| SCHEMBL11581548 | 0.87 | ADORA2A (0.50) | ADORA2APTPRCBRD4PIM1ALDH1A1 | |
| SCHEMBL1764840 | 0.85 | ADORA2A (0.66) | ADORA2AKCNA3MAPTPOLBKMT2A | |
| SCHEMBL10927218 | 0.85 | ADORA2A (0.60) | ADORA2AKCNA3BRD4MAPTPOLB | |
| SCHEMBL10488130 | 0.84 | ADORA2A (0.58) | ADORA2APTPRCKCNA3BRD4MAPT | |
| SCHEMBL10488039 | 0.84 | ADORA2A (0.58) | ADORA2APTPRCKCNA3BRD4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4126626-A | DYES, POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1978-11-21 | — | — | US | disclosed |