Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | HNF4A | P41235 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 2/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7879462 | 0.81 | HTT (0.48) | FFAR1TMPRSS4MEN1KMT2AHTT | |
| SCHEMBL11066386 | 0.80 | HSP90AB1 (0.47) | TMPRSS4HNF4AMEN1KMT2AXDH | |
| SCHEMBL30902488 | 0.79 | HNF4A (0.62) | TMPRSS4HNF4AMEN1KMT2AHTT | |
| SCHEMBL131551 | 0.79 | HNF4A (0.62) | TMPRSS4HNF4AMEN1KMT2AHTT | |
| SCHEMBL11581723 | 0.78 | FFAR1 (0.46) | FFAR1HNF4AMEN1KMT2AHTT | |
| Methane SCHEMBL2468798 | 0.78 | HNF4A (0.61) | TMPRSS4HNF4AMEN1KMT2AHTT | |
| SCHEMBL2935246 | 0.75 | CA1 (0.61) | TMPRSS4MEN1KMT2AHTTP2RX1 | |
| SCHEMBL11582937 | 0.75 | MEN1 (0.61) | MEN1KMT2AHTTNR4A2 | |
| SCHEMBL11581510 | 0.75 | KMT2A (0.72) | MEN1KMT2AHTT | |
| SCHEMBL11654727 | 0.75 | HPGD (0.58) | MEN1KMT2AHTTEGLN1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4111936-A | PYRIDAZINETHIONES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1978-09-05 | — | — | US | disclosed |