SCHEMBL11581985

SCHEMBL11581985

Cc1ccccc1CC(C)NC(=O)Nc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.53
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
MAPT P10636 3/20 0.52
RAB9A P51151 7/20 0.51
NPC1 O15118 5/20 0.51
HTT P42858 2/20 0.51
EPHX2 P34913 3/20 0.49
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
LMNA P02545 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
TP53 P04637 1/20 0.46
EPHX1 P07099 1/20 0.46
TSHR P16473 1/20 0.46
CDK9 P50750 1/20 0.46
CLK4 Q9HAZ1 1/20 0.46
CASP3 P42574 1/20 0.45
SENP7 Q9BQF6 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11582204 0.92 RAB9A (0.50) HSD17B10MEN1KMT2AMAPTRAB9A
SCHEMBL11583644 0.88 KMT2A (0.66) HSD17B10MEN1KMT2AMAPTRAB9A
SCHEMBL11581999 0.86 TSHR (0.54) MEN1KMT2AMAPTRAB9ANPC1
SCHEMBL11582211 0.82 MAPT (0.48) HSD17B10MAPTRAB9ANPC1HTT
SCHEMBL11580858 0.81 NPC1 (0.77) HSD17B10MEN1KMT2AMAPTRAB9A
SCHEMBL1492689 0.80 PSEN1 (0.55)
SCHEMBL11583190 0.80 BRD4 (0.49) HSD17B10MEN1KMT2AMAPTRAB9A
SCHEMBL11583182 0.80 MAPK1 (0.55) MEN1KMT2AMAPTRAB9AHTT
SCHEMBL12813567 0.80 ACACB (0.53) MEN1KMT2ARAB9ANPC1KDM4E
SCHEMBL11580811 0.79 NPC1 (0.64) HSD17B10MEN1KMT2AMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4078913-A Herbicidal 3-(2-phenylisopropyl)urea derivatives S.D.S. BIOTECH KABUSHIKI KAISHA, 1978-03-14 US disclosed