SCHEMBL11583189

SCHEMBL11583189

Cc1cc(=O)oc2nc(N(C)C)ccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.43
IGLV6-57 P01721 3/20 0.42
ALDH1A1 P00352 8/20 0.41
HSD17B10 Q99714 7/20 0.41
KDM4E B2RXH2 7/20 0.41
HPGD P15428 6/20 0.41
GAA P10253 4/20 0.41
GLA P06280 3/20 0.41
CASP1 P29466 3/20 0.41
CASP7 P55210 3/20 0.41
CYP1A2 P05177 3/20 0.41
LMNA P02545 3/20 0.41
MCL1 Q07820 3/20 0.41
CA12 O43570 2/20 0.41
CA9 Q16790 2/20 0.41
MAOB P27338 2/20 0.41
CYP2C9 P11712 1/20 0.41
AKR1B1 P15121 1/20 0.41
UGT1A1 P22309 1/20 0.41
KDR P35968 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25272932 0.82 KCNA3 (0.46) KMT2AALDH1A1HSD17B10KDM4EHPGD
SCHEMBL11582068 0.77 KDM4E (0.51) KMT2AALDH1A1HSD17B10KDM4EHPGD
SCHEMBL11581378 0.70 MCL1 (0.44) KMT2AALDH1A1HSD17B10KDM4EHPGD
SCHEMBL25227213 0.69 KCNA3 (0.43) KMT2AIGLV6-57ALDH1A1HSD17B10KDM4E
SCHEMBL3007792 0.68 HPGD (0.49) KMT2AALDH1A1HSD17B10KDM4EHPGD
SCHEMBL30017080 0.68 KDM4E (0.42) KMT2AALDH1A1HSD17B10KDM4EHPGD
SCHEMBL28155644 0.68 CYP1A2 (0.60) KMT2AALDH1A1HSD17B10KDM4EHPGD
SCHEMBL11591247 0.68 NQO2 (0.44) ALDH1A1HSD17B10KDM4EHPGDGAA
SCHEMBL67970 0.67 IGLV6-57 (0.72) IGLV6-57ALDH1A1HSD17B10KDM4EHPGD
SCHEMBL29401382 0.67 IGLV6-57 (0.72) IGLV6-57ALDH1A1HSD17B10KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4103256-A BLUE-GREEN TO NEAR ULTRAVIOLET THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1978-07-25 US claimed
US-4103256-A BLUE-GREEN TO NEAR ULTRAVIOLET THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1978-07-25 US disclosed