Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 6/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11581629 | 0.87 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL27963570 | 0.81 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL26816407 | 0.79 | KDM4E (0.55) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL31489987 | 0.75 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL11453544 | 0.74 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL11153748 | 0.74 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL11158499 | 0.74 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL11164954 | 0.72 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL27963634 | 0.72 | KDM4E (0.41) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL11347937 | 0.71 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4087561-A | Control of nitrosamine formation in nitride cured meat with 1,2,3,4-tetrahydro-quinoline compounds | CANADA PACKERS LIMITED (CA) | 1978-05-02 | — | — | US | disclosed |
| US-4079153-A | SUPPRESSING FORMATION OF NITROSAMINES BY INTRODUCING A 1,2-DIHYDROQUINOLINE INTO MEAT | LEVER BROTHERS COMPANY (US) | 1978-03-14 | — | — | US | disclosed |