Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 6/20 | 0.63 |
| ▸ | HTR2A | P28223 | 5/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | CASR | P41180 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11679630 | 0.98 | HRH1 (0.61) | HRH1HTR2AKCNH2CHRM2CHRM1 | |
| SCHEMBL13900375 | 0.88 | HRH1 (0.61) | HRH1HTR2AKCNH2CHRM2CHRM1 | |
| SCHEMBL22957833 | 0.77 | RIPK1 (0.58) | HRH1HTR2AKCNH2CHRM2CHRM1 | |
| SCHEMBL30582770 | 0.77 | MTOR (0.57) | HRH1KCNH2CHRM2CHRM1ADRA1A | |
| Hydrochloric Acid SCHEMBL11389802 | 0.76 | HTR2A (0.96) | HRH1HTR2AKCNH2CHRM2CHRM1 | |
| SCHEMBL16368620 | 0.76 | RIPK1 (0.59) | HRH1HTR2ASLC6A4LMNACYP2D6 | |
| SCHEMBL12205817 | 0.75 | HRH1 (0.52) | HRH1HTR2AKCNH2CHRM2CHRM1 | |
| SCHEMBL11583588 | 0.74 | HTR2A (0.66) | HRH1HTR2AKCNH2CHRM2CHRM1 | |
| SCHEMBL9073997 | 0.73 | HRH1 (0.71) | HRH1HTR2AKCNH2CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL11679206 | 0.73 | HTR2A (0.63) | HRH1HTR2AKCNH2CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4098890-A | METHOD FOR TREATING ARRHYTHMIA | ELI LILLY AND COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4034011-A | 1,1-Diphenyl-4-(substituted-amino)butanes | ELI LILLY AND COMPANY (US) | 1977-07-05 | — | — | US | disclosed |
| US-3987201-A | ARYL AMINES | ELI LILLY AND COMPANY (US) | 1976-10-19 | — | — | US | disclosed |