Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.65 |
| ▸ | HRH1 | P35367 | 9/20 | 0.58 |
| ▸ | HTR2A | P28223 | 7/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11585784 | 0.94 | HRH1 (0.66) | SIGMAR1HRH1HTR2ACHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL11679345 | 0.92 | HRH1 (0.63) | SIGMAR1HRH1HTR2ACHRM2CHRM1 | |
| Acetic Acid SCHEMBL11680239 | 0.86 | HRH1 (0.56) | SIGMAR1HRH1HTR2ACHRM2CHRM1 | |
| Diisopromine SCHEMBL25648 | 0.86 | HRH1 (0.63) | SIGMAR1HRH1HTR2ACHRM2CHRM1 | |
| SCHEMBL27745390 | 0.84 | CHRM3 (0.59) | SIGMAR1HRH1HTR2ACHRM2CHRM1 | |
| SCHEMBL27745393 | 0.84 | CHRM3 (0.59) | SIGMAR1HRH1HTR2ACHRM2CHRM1 | |
| Diisopromine SCHEMBL11582569 | 0.84 | HRH1 (0.61) | SIGMAR1HRH1HTR2ACHRM2CHRM1 | |
| SCHEMBL11584246 | 0.80 | HTR2A (0.88) | SIGMAR1HRH1HTR2ACHRM2CHRM1 | |
| SCHEMBL11583133 | 0.80 | CYP19A1 (0.46) | SIGMAR1HRH1HTR2ACHRM2CHRM1 | |
| SCHEMBL27514441 | 0.80 | CHRM3 (0.64) | SIGMAR1HRH1HTR2ACHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4098890-A | METHOD FOR TREATING ARRHYTHMIA | ELI LILLY AND COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-3987201-A | ARYL AMINES | ELI LILLY AND COMPANY (US) | 1976-10-19 | — | — | US | disclosed |