Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.88 |
| ▸ | HRH1 | P35367 | 6/20 | 0.88 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | SCN1A | P35498 | 2/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11755782 | 0.96 | HTR2A (0.81) | HTR2AHRH1SIGMAR1TDP1CHRM2 | |
| Hydrochloric Acid SCHEMBL11374749 | 0.92 | HTR2A (0.96) | HTR2AHRH1SIGMAR1TDP1CHRM2 | |
| SCHEMBL17942920 | 0.87 | HTR2A (0.67) | HTR2AHRH1SIGMAR1CHRM2SLC6A2 | |
| SCHEMBL1802493 | 0.85 | HRH1 (1.00) | HTR2AHRH1SIGMAR1TDP1CHRM2 | |
| Hydrochloric Acid SCHEMBL11383046 | 0.83 | HRH1 (0.95) | HTR2AHRH1SIGMAR1TDP1CHRM2 | |
| SCHEMBL9073997 | 0.82 | HRH1 (0.71) | HTR2AHRH1SIGMAR1CHRM2SLC6A2 | |
| SCHEMBL11584337 | 0.80 | SIGMAR1 (0.65) | HTR2AHRH1SIGMAR1TDP1CHRM2 | |
| SCHEMBL11582720 | 0.80 | SIGMAR1 (0.76) | HTR2AHRH1SIGMAR1OPRM1DRD3 | |
| Hydrochloric Acid SCHEMBL1123516 | 0.80 | HTR2A (0.58) | HTR2AHRH1SIGMAR1TDP1CHRM2 | |
| SCHEMBL8141129 | 0.79 | HTR2A (0.72) | HTR2AHRH1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4098890-A | METHOD FOR TREATING ARRHYTHMIA | ELI LILLY AND COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-3987201-A | ARYL AMINES | ELI LILLY AND COMPANY (US) | 1976-10-19 | — | — | US | disclosed |