Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.60 |
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | HPGD | P15428 | 5/20 | 0.60 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.60 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.60 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.60 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.60 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.60 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11585091 | 1.00 | TDP1 (0.60) | TDP1MAPTHPGDNR1I2CTDSP1 | |
| SCHEMBL11585962 | 0.95 | TDP1 (0.55) | TDP1MAPTHPGDNR1I2CTDSP1 | |
| SCHEMBL7040792 | 0.92 | TDP1 (0.61) | TDP1MAPTHPGDNR1I2CTDSP1 | |
| SCHEMBL7030196 | 0.92 | TDP1 (0.61) | TDP1MAPTHPGDNR1I2CTDSP1 | |
| SCHEMBL11063940 | 0.92 | TDP1 (0.61) | TDP1MAPTHPGDNR1I2CTDSP1 | |
| SCHEMBL7028779 | 0.92 | TDP1 (0.61) | TDP1MAPTHPGDNR1I2CTDSP1 | |
| SCHEMBL9436142 | 0.92 | TDP1 (0.61) | TDP1MAPTHPGDNR1I2CTDSP1 | |
| SCHEMBL14065430 | 0.92 | TDP1 (0.62) | TDP1MAPTHPGDNR1I2CTDSP1 | |
| SCHEMBL11674593 | 0.92 | TDP1 (0.62) | TDP1MAPTHPGDNR1I2CTDSP1 | |
| SCHEMBL11471537 | 0.92 | TDP1 (0.60) | TDP1MAPTHPGDNR1I2CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4110534-A | PROCESS FOR THE PREPARATION OF 3-VINYL AND SUBSTITUTED VINYL CEPHALOSPORINS | GLAXO LABORATORIES LIMITED (GB) | 1978-08-29 | — | — | US | disclosed |
| US-4107431-A | ANTIBIOTICS | GLAXO LABORATORIES LIMITED (GB) | 1978-08-15 | — | — | US | disclosed |