Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | TYR | P14679 | 2/20 | 0.51 |
| ▸ | APP | P05067 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11585649 | 1.00 | MAPT (0.53) | MAPTKDM4EALDH1A1HTTNPSR1 | |
| Maleic Acid SCHEMBL11586744 | 0.92 | KDM4E (0.58) | MAPTKDM4EALDH1A1HTTNPSR1 | |
| Maleic Acid SCHEMBL11586747 | 0.92 | KDM4E (0.58) | MAPTKDM4EALDH1A1HTTNPSR1 | |
| SCHEMBL11585626 | 0.88 | APP (0.57) | MAPTKDM4EALDH1A1APPTTR | |
| SCHEMBL11585622 | 0.88 | APP (0.57) | MAPTKDM4EALDH1A1APPTTR | |
| SCHEMBL11585613 | 0.84 | ALDH1A1 (0.51) | MAPTKDM4EALDH1A1NPSR1HPGD | |
| SCHEMBL11585615 | 0.84 | ALDH1A1 (0.51) | MAPTKDM4EALDH1A1NPSR1HPGD | |
| Maleic Acid SCHEMBL11588067 | 0.82 | ALDH1A1 (0.56) | MAPTKDM4EALDH1A1HPGDAPP | |
| Maleic Acid SCHEMBL11588068 | 0.82 | ALDH1A1 (0.56) | MAPTKDM4EALDH1A1HPGDAPP | |
| SCHEMBL3364855 | 0.82 | APP (0.62) | MAPTKDM4EALDH1A1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4115398-A | CARDIOVASCULAR DISORDERS | KOWA COMPANY LTD. (JP) | 1978-09-19 | — | — | US | disclosed |