SCHEMBL11585697

SCHEMBL11585697

CC=CCC(C(C)=O)C1(C)OC1Cl

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.30
GRIK2 Q13002 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11585691 1.00 GRIK1 (0.30) GRIK1GRIK2
SCHEMBL11585620 0.76
SCHEMBL11585616 0.76
SCHEMBL10870577 0.64 GRIK1 (0.47) GRIK1GRIK2
SCHEMBL10871217 0.64 GRIK1 (0.47) GRIK1GRIK2
SCHEMBL11861283 0.63 GRIK1 (0.45) GRIK1GRIK2
SCHEMBL11861273 0.63 GRIK1 (0.45) GRIK1GRIK2
SCHEMBL6494908 0.61
SCHEMBL6504441 0.61
SCHEMBL5746258 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4071542-A Synthesis of hydroxycyclopenten-1-ones HOFFMANN-LA ROCHE INC. (US) 1978-01-31 US claimed
US-4071542-A Synthesis of hydroxycyclopenten-1-ones HOFFMANN-LA ROCHE INC. (US) 1978-01-31 US disclosed
US-4032577-A UNSATURATED KETONES HOFFMANN-LA ROCHE INC. (US) 1977-06-28 US disclosed
US-3978093-A Synthesis of hydroxycyclopenten-1-ones HOFFMANN-LA ROCHE INC. (US) 1976-08-31 US disclosed