Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 4/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10871217 | 1.00 | GRIK1 (0.47) | GRIK1GRIK2FNTAFNTBCTSK | |
| SCHEMBL11861273 | 0.90 | GRIK1 (0.45) | GRIK1GRIK2FNTAFNTBCTSK | |
| SCHEMBL11861283 | 0.90 | GRIK1 (0.45) | GRIK1GRIK2FNTAFNTBCTSK | |
| SCHEMBL11857180 | 0.90 | GRIK1 (0.54) | GRIK1GRIK2FNTAFNTBCTSK | |
| SCHEMBL2917234 | 0.90 | GRIK1 (0.54) | GRIK1GRIK2FNTAFNTBCTSK | |
| SCHEMBL8675865 | 0.79 | CTSK (0.37) | GRIK1GRIK2FNTAFNTBCTSK | |
| SCHEMBL8675866 | 0.79 | CTSK (0.37) | GRIK1GRIK2FNTAFNTBCTSK | |
| SCHEMBL10870370 | 0.77 | ALDH1A1 (0.38) | GRIK1GRIK2CTSK | |
| SCHEMBL10870498 | 0.77 | ALDH1A1 (0.38) | GRIK1GRIK2CTSK | |
| SCHEMBL10870379 | 0.77 | ALDH1A1 (0.38) | GRIK1GRIK2CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186275-A2 | 2-Substituted amino-4(1H)-pyrimidone derivatives, their production, and medical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-07-02 | — | — | EP | disclosed |