Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | IAPP | P10997 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GPR183 | P32249 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11121090 | 0.85 | MAOB (0.61) | TDP1GLAIAPPPTGS1MAOB | |
| SCHEMBL11121092 | 0.85 | MAOB (0.61) | TDP1GLAIAPPPTGS1MAOB | |
| SCHEMBL13893105 | 0.84 | F3 (0.57) | TDP1MAOBLMNATSHRALDH1A1 | |
| SCHEMBL1359336 | 0.83 | GLA (0.77) | TDP1GLAIAPPPTGS1MAOB | |
| SCHEMBL1359335 | 0.83 | GLA (0.77) | TDP1GLAIAPPPTGS1MAOB | |
| SCHEMBL23088918 | 0.83 | CA2 (0.56) | TDP1GLAIAPPPTGS1ALDH1A1 | |
| SCHEMBL10458770 | 0.82 | TDP1 (0.53) | TDP1MAOBLMNAGAATSHR | |
| SCHEMBL8751739 | 0.82 | HCAR2 (0.59) | TDP1GLAAPPLMNAGAA | |
| SCHEMBL8751736 | 0.82 | HCAR2 (0.59) | TDP1GLAAPPLMNAGAA | |
| SCHEMBL10458771 | 0.82 | TDP1 (0.53) | TDP1MAOBLMNAGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4118289-A | BRIGHTENER SYSTEM OF A NONIONIC SURFACTANT, AN ALIPHATIC ALDEHYDE, AN AMINE AND A HETEROCYCLIC ALDEHYDE OR AROMATIC KETONE OR CARBOXY ACID | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1978-10-03 | — | — | US | disclosed |