Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Pyrophosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.91 |
| ▸ | BLM | P54132 | 1/20 | 0.91 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.91 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | INPPL1 | O15357 | 2/20 | 0.35 |
| ▸ | INPP5A | Q14642 | 2/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.35 |
| ▸ | INPP5B | P32019 | 1/20 | 0.35 |
| ▸ | BTN3A1 | O00481 | 2/20 | 0.35 |
| ▸ | ITPR3 | Q14573 | 3/20 | 0.33 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.33 |
| ▸ | ITPR2 | Q14571 | 1/20 | 0.33 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrophosphoric Acid SCHEMBL29634664 | 0.95 | — | — | |
| Pyrophosphoric Acid SCHEMBL8851914 | 0.95 | FDPS (1.00) | FDPSBLMTDP1CA4CA2 | |
| Pyrophosphoric Acid SCHEMBL292348 | 0.95 | FDPS (1.00) | FDPSBLMTDP1CA4CA2 | |
| Pyrophosphoric Acid SCHEMBL3654 | 0.95 | — | — | |
| Pyrophosphoric Acid SCHEMBL5512168 | 0.92 | FDPS (0.77) | FDPSBLMTDP1CA4CA2 | |
| Pyrophosphoric Acid SCHEMBL23537580 | 0.91 | FDPS (0.91) | FDPSBLMTDP1CA4CA2 | |
| Pyrophosphoric Acid SCHEMBL1680134 | 0.91 | FDPS (0.91) | FDPSBLMTDP1CA4CA2 | |
| Pyrophosphoric Acid SCHEMBL145674 | 0.91 | FDPS (0.91) | FDPSBLMTDP1CA4CA2 | |
| Pyrophosphoric Acid SCHEMBL21433694 | 0.91 | FDPS (0.91) | FDPSBLMTDP1CA4CA2 | |
| Pyrophosphoric Acid SCHEMBL21145230 | 0.91 | FDPS (0.91) | FDPSBLMTDP1CA4CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116005214-A | Method for ultrasonic plating of Sn-Ag salient points under high current density | 云南锡业集团（控股）有限责任公司研发中心 | 2023-04-25 | — | — | CN | claimed |
| CN-112351974-B | Novel compound 2-amino-2- (1, 2, 3-triazole-4-yl) -1, 3-propanediol derivative capable of directly inhibiting ASM activity and application thereof | 庆北大学校产学协力团 | 2024-01-26 | — | — | CN | disclosed |
| CN-116940357-A | Composition for preventing or treating metabolic diseases comprising torasemide and cromolyn | 昂科克罗斯株式会社 | 2023-10-24 | — | — | CN | disclosed |
| CN-116005214-A | Method for ultrasonic plating of Sn-Ag salient points under high current density | 云南锡业集团（控股）有限责任公司研发中心 | 2023-04-25 | — | — | CN | disclosed |
| CN-112351974-A | Novel compound 2-amino-2- (1,2, 3-triazole-4-yl) -1, 3-propylene glycol derivative for directly inhibiting ASM activity and application thereof | 庆北大学校产学协力团 | 2021-02-09 | — | — | CN | disclosed |
| US-4083764-A | SILVER-IODINE PYROPHOSPHATE COATED WITH SILVER HALIDE OR SILVER PHOSPHATE | U.S. PHILIPS CORPORATION (US) | 1978-04-11 | — | — | US | disclosed |