Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.35 |
| ▸ | MEN1 | O00255 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11136344 | 0.91 | ALDH1A1 (0.41) | MAPTMAPK1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL11586691 | 0.88 | MAPT (0.41) | MAPTMAPK1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL11587398 | 0.88 | MEN1 (0.43) | MAPTMAPK1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL11589623 | 0.86 | ALDH1A1 (0.42) | MAPTMAPK1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL11588348 | 0.84 | MAPT (0.42) | MAPTMAPK1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL11589544 | 0.83 | MAPT (0.41) | MAPTMAPK1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL11587740 | 0.83 | ALDH1A1 (0.43) | MAPTMAPK1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL11586987 | 0.82 | MAPT (0.40) | MAPTMAPK1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL10797274 | 0.82 | KMT2A (0.45) | MAPTMAPK1TDP1L3MBTL1RAPGEF4 | |
| SCHEMBL11593158 | 0.82 | MAPT (0.47) | MAPTMAPK1TDP1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4084004-A | Rodenticidal use of diphenylamines | ELI LILLY AND COMPANY (US) | 1978-04-11 | — | — | US | disclosed |