Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL756292 | 0.98 | LMNA (0.45) | LMNAKCNN4MIFCYP1A2CYP3A4 | |
| SCHEMBL11588095 | 0.96 | LMNA (0.43) | LMNAKCNN4MIFCYP1A2CYP3A4 | |
| SCHEMBL6738852 | 0.82 | AOC3 (0.41) | LMNAKCNN4MEN1KMT2ANPC1 | |
| SCHEMBL28248384 | 0.81 | LMNA (0.45) | LMNAKCNN4MIFCYP1A2CYP3A4 | |
| SCHEMBL9077582 | 0.79 | LMNA (0.43) | LMNAKCNN4MIFCYP1A2CYP3A4 | |
| Phosphine SCHEMBL10951511 | 0.79 | LMNA (0.43) | LMNAKCNN4MIFCYP1A2CYP3A4 | |
| SCHEMBL1176305 | 0.79 | LMNA (0.43) | LMNAKCNN4MIFCYP1A2CYP3A4 | |
| SCHEMBL7760569 | 0.79 | POLB (0.41) | LMNAMEN1KMT2ANPC1POLB | |
| SCHEMBL5072327 | 0.78 | LMNA (0.42) | LMNAKCNN4MIFCYP1A2CYP3A4 | |
| SCHEMBL2679440 | 0.78 | LMNA (0.42) | LMNAKCNN4MIFCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4092268-A | POLYMERIZATION CATALYST OF AN ORGANO-LITHIUM INITIATOR, A BARIUM OR STRONTIUM COMPOUND, AND AN ORGANOMETALLIC ALUMINUM OR ZINC COMPOUND | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN, RAISON SOCIALE MICHELIN & CIE (FR) | 1978-05-30 | — | — | US | claimed |
| US-4080492-A | ORGANOLITHIUM INITIATOR AND COCATALYST CONTAINING BARIUM OR STRONTIUM | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 1978-03-21 | — | — | US | claimed |