Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCH | P24723 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL718113 | 0.91 | PRKCH (0.38) | PRKCHPRKCEPIK3CDPDE4APDE4B | |
| SCHEMBL10081 | 0.84 | PIK3CD (0.42) | PRKCHPRKCEPIK3CDPDE4APDE4B | |
| SCHEMBL17530776 | 0.82 | PIK3CD (0.47) | PIK3CDPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL714424 | 0.80 | PIK3CD (0.42) | PIK3CDPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11674 | 0.79 | PRKCH (0.37) | PRKCHPRKCEPIK3CDPDE4APDE4B | |
| SCHEMBL11673 | 0.79 | PRKCH (0.37) | PRKCHPRKCEPIK3CDPDE4APDE4B | |
| SCHEMBL716764 | 0.78 | PIK3CD (0.48) | PRKCHPRKCEPIK3CDKDM4EDPP4 | |
| SCHEMBL718038 | 0.78 | PIK3CD (0.35) | PRKCHPRKCEPIK3CDPDE4APDE4B | |
| SCHEMBL17530777 | 0.74 | PRKCH (0.35) | PRKCHPRKCEPDE4APDE4BPDE4C | |
| SCHEMBL713514 | 0.74 | PIK3CD (0.48) | PRKCHPRKCEPIK3CDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2499129-A1 | QUINOLINE AND QUINOXALINE DERIVATIVES AS KINASE INHIBITORS | UCB Pharma, S.A. (BE) | 2012-09-19 | — | — | EP | disclosed |
| WO-2011058108-A1 | QUINOLINE AND QUINOXALINE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2011-05-19 | — | — | WO | disclosed |