Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2203384 | 0.92 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1MAPTNPSR1HTT | |
| SCHEMBL12732185 | 0.84 | PDE4B (0.58) | SMN1; SMN2ALDH1A1MAPTNPSR1CA1 | |
| SCHEMBL26812628 | 0.80 | SMN1; SMN2 (0.70) | SMN1; SMN2ALDH1A1MAPTNPSR1HTT | |
| SCHEMBL11432604 | 0.77 | MAPT (0.55) | SMN1; SMN2ALDH1A1MAPTNPSR1HTT | |
| SCHEMBL13950336 | 0.76 | ALDH1A1 (0.60) | SMN1; SMN2ALDH1A1MAPTNPSR1HTT | |
| SCHEMBL14202653 | 0.76 | PDE4B (0.52) | SMN1; SMN2ALDH1A1MAPTNPSR1HTT | |
| SCHEMBL14229501 | 0.76 | PDE4B (0.52) | SMN1; SMN2ALDH1A1MAPTNPSR1HTT | |
| SCHEMBL12732158 | 0.76 | CA1 (0.60) | SMN1; SMN2ALDH1A1NPSR1HTTCA1 | |
| SCHEMBL14354708 | 0.76 | ALDH1A1 (0.59) | SMN1; SMN2ALDH1A1MAPTNPSR1HTT | |
| SCHEMBL19053365 | 0.73 | SMN1; SMN2 (0.78) | SMN1; SMN2ALDH1A1MAPTNPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4115124-A | WITH POLYVINYLIMIDAZOLE | EASTMAN KODAK COMPANY (US) | 1978-09-19 | — | — | US | disclosed |
| US-4106941-A | PHOTOSTABILITY | EASTMAN KODAK COMPANY (US) | 1978-08-15 | — | — | US | disclosed |