Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11596631 | 0.95 | ALDH1A1 (0.41) | ALDH1A1MAPTHTTNSD2GAA | |
| SCHEMBL11594691 | 0.85 | MAPT (0.47) | ALDH1A1MAPTNSD2GAAPLCG1 | |
| SCHEMBL10778005 | 0.84 | ALDH1A1 (0.41) | ALDH1A1MAPTHTTKDM4ELMNA | |
| SCHEMBL7521818 | 0.84 | GAA (0.45) | ALDH1A1MAPTHTTNSD2GAA | |
| SCHEMBL9011781 | 0.83 | ALDH1A1 (0.42) | ALDH1A1MAPTHTTKDM4ELMNA | |
| SCHEMBL11596939 | 0.82 | MAPT (0.46) | ALDH1A1MAPTNSD2GAAPLCG1 | |
| SCHEMBL11597174 | 0.82 | GAA (0.41) | ALDH1A1MAPTNSD2GAAPLCG1 | |
| SCHEMBL11593851 | 0.80 | MAPT (0.47) | ALDH1A1MAPTNSD2GAAPLCG1 | |
| SCHEMBL11596026 | 0.79 | ALDH1A1 (0.48) | ALDH1A1MAPTHTTKDM4ELMNA | |
| SCHEMBL11237924 | 0.78 | GAA (0.45) | ALDH1A1MAPTHTTNSD2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4118232-A | Photographic material containing sulphonic acid group containing disazo dyestuffs | CIBA-GEIGY AG (CH) | 1978-10-03 | — | — | US | disclosed |
| US-4051123-A | Sulfonic-acid-group containing disazo dyestuffs | CIBA-GEIGY AG (CH) | 1977-09-27 | — | — | US | disclosed |