Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIMP3 | P35625 | 6/20 | 0.67 |
| ▸ | RECQL | P46063 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | APEX1 | P27695 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | PKM | P14618 | 5/20 | 0.53 |
| ▸ | P2RX1 | P51575 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.53 |
| ▸ | BLM | P54132 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | BRCA1 | P38398 | 3/20 | 0.53 |
| ▸ | STAT1 | P42224 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11440620 | 0.95 | TIMP3 (0.61) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL11438261 | 0.94 | TIMP3 (0.60) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL11581452 | 0.89 | TIMP3 (0.53) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL11438115 | 0.89 | TIMP3 (0.69) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL11514021 | 0.88 | TIMP3 (0.72) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL11593852 | 0.87 | TIMP3 (0.57) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL11597795 | 0.87 | APEX1 (0.69) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL11595543 | 0.86 | TIMP3 (0.56) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL11411315 | 0.86 | TIMP3 (0.61) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL11436257 | 0.86 | APEX1 (0.53) | TIMP3RECQLKMT2AHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4129591-A | INHIBITORS OF THE COMPLEMENT SYSTEM | AMERICAN CYANAMID COMPANY (US) | 1978-12-12 | — | — | US | disclosed |