SCHEMBL11596038

SCHEMBL11596038

CC(=O)c1cccc(C(=O)O)c1OCc1cccc(Br)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 9/20 0.61
MAOA P21397 3/20 0.61
ESR1 P03372 1/20 0.54
NR3C1 P04150 1/20 0.54
PGR P06401 1/20 0.54
NR3C2 P08235 1/20 0.54
AR P10275 1/20 0.54
THRA P10827 1/20 0.54
THRB P10828 1/20 0.54
MRGPRX4 Q96LA9 2/20 0.51
FFAR1 O14842 1/20 0.49
FFAR4 Q5NUL3 1/20 0.49
PARP15 Q460N3 3/20 0.48
PARP10 Q53GL7 2/20 0.48
PARP14 Q460N5 1/20 0.48
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
HCAR2 Q8TDS4 1/20 0.46
HPD P32754 1/20 0.46
RECQL P46063 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6895382 0.88 MAOB (0.60) MAOBMAOAESR1NR3C1PGR
SCHEMBL8980650 0.86 MAOB (0.54) MAOBMEN1KMT2A
SCHEMBL11470293 0.81 MAOB (0.58) MAOBMAOAESR1NR3C1PGR
SCHEMBL1120930 0.79 MAOB (0.56) MAOBMAOAESR1NR3C1PGR
SCHEMBL1221635 0.79 MAOB (0.53) MAOBMAOAESR1NR3C1PGR
SCHEMBL28642765 0.79 PARP1 (0.59) MAOBMAOAMRGPRX4FFAR1FFAR4
SCHEMBL30575486 0.79 PARP1 (0.59) MAOBMAOAMRGPRX4FFAR1FFAR4
SCHEMBL6074417 0.78 MAOB (0.49) MAOBMAOAESR1NR3C1PGR
SCHEMBL15716510 0.77 ALDH1A1 (0.58) THRATHRBMEN1KMT2A
SCHEMBL1097135 0.77 MAOB (0.62) MAOBMAOAESR1NR3C1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4101579-A Phenethanolamine ethers ALLEN & HANBURYS LIMITED (GB) 1978-07-18 US disclosed