Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 16/20 | 0.50 |
| ▸ | PPARD | Q03181 | 8/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11597072 | 0.86 | PPARA (0.50) | CYP2C19PPARAPPARDKDM4EGAA | |
| SCHEMBL11595888 | 0.84 | PPARA (0.54) | CYP2C19PPARAPPARDKDM4ESMN1; SMN2 | |
| SCHEMBL11596959 | 0.84 | PPARD (0.46) | CYP2C19PPARAPPARDKDM4EGAA | |
| SCHEMBL11596113 | 0.82 | PPARA (0.51) | CYP2C19PPARAPPARDKDM4EGAA | |
| SCHEMBL11598181 | 0.81 | MCL1 (0.47) | CYP2C19PPARAPPARDKDM4EGAA | |
| SCHEMBL11595598 | 0.80 | PPARA (0.55) | CYP2C19PPARAPPARDKDM4ESMN1; SMN2 | |
| SCHEMBL11597880 | 0.79 | CYP2C19 (0.49) | CYP2C19PPARAPPARDKDM4EGAA | |
| SCHEMBL11597279 | 0.79 | PPARD (0.50) | CYP2C19PPARAPPARDKDM4EPPARG | |
| SCHEMBL11598665 | 0.79 | PPARA (0.46) | CYP2C19PPARAPPARDKDM4EPPARG | |
| SCHEMBL11596932 | 0.79 | PPARA (0.52) | CYP2C19PPARAPPARDSMN1; SMN2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4125732-A | HYPOLIPIDEMIC | AMERICAN CYANAMID COMPANY (US) | 1978-11-14 | — | — | US | disclosed |