Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 5/20 | 0.49 |
| ▸ | PPARD | Q03181 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | FABP2 | P12104 | 2/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11597072 | 0.96 | PPARA (0.50) | PPARAKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL11595598 | 0.96 | PPARA (0.55) | PPARAKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL11596999 | 0.93 | SMN1; SMN2 (0.57) | PPARAKMT2AMEN1SMN1; SMN2PPARG | |
| SCHEMBL11595796 | 0.92 | PPARA (0.51) | PPARAKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL11595888 | 0.92 | PPARA (0.54) | PPARAKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL11596810 | 0.90 | PPARA (0.51) | PPARAKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL11596932 | 0.86 | PPARA (0.52) | PPARAKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL11598113 | 0.85 | PPARA (0.55) | PPARAKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL11596959 | 0.84 | PPARD (0.46) | PPARAKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL11598533 | 0.84 | PPARA (0.44) | PPARAKMT2AMEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4125732-A | HYPOLIPIDEMIC | AMERICAN CYANAMID COMPANY (US) | 1978-11-14 | — | — | US | disclosed |