Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11596113 | 0.93 | PPARA (0.51) | SMN1; SMN2POLBRAB9ANPC1CASP3 | |
| SCHEMBL11597072 | 0.89 | PPARA (0.50) | SMN1; SMN2POLBRAB9ANPC1CASP3 | |
| SCHEMBL11595598 | 0.88 | PPARA (0.55) | SMN1; SMN2POLBNPC1KDM4EKMT2A | |
| SCHEMBL11595796 | 0.84 | PPARA (0.51) | SMN1; SMN2POLBRAB9ANPC1CASP3 | |
| SCHEMBL11595888 | 0.84 | PPARA (0.54) | SMN1; SMN2NPC1KDM4EKMT2AMEN1 | |
| SCHEMBL11598544 | 0.84 | PPARG (0.49) | SMN1; SMN2POLBRAB9ANPC1CASP3 | |
| SCHEMBL11596810 | 0.82 | PPARA (0.51) | SMN1; SMN2KMT2AMEN1ALDH1A1PPARA | |
| SCHEMBL11595646 | 0.82 | SMN1; SMN2 (0.48) | SMN1; SMN2POLBRAB9ANPC1CASP3 | |
| SCHEMBL11596932 | 0.78 | PPARA (0.52) | SMN1; SMN2KMT2AMEN1ALDH1A1PPARA | |
| SCHEMBL10959273 | 0.78 | SMN1; SMN2 (0.60) | SMN1; SMN2POLBRAB9ANPC1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4125732-A | HYPOLIPIDEMIC | AMERICAN CYANAMID COMPANY (US) | 1978-11-14 | — | — | US | disclosed |