Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 12/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | PLD2 | O14939 | 3/20 | 0.46 |
| ▸ | PLD1 | Q13393 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1152842 | 0.90 | CHRM1 (0.61) | CHRM1DRD2OPRM1PLD2PLD1 | |
| SCHEMBL11594936 | 0.86 | CHRM1 (0.57) | CHRM1DRD2OPRM1PLD2PLD1 | |
| SCHEMBL11595730 | 0.86 | CHRM1 (0.55) | CHRM1DRD2OPRM1PLD2PLD1 | |
| SCHEMBL11595640 | 0.86 | CHRM1 (0.59) | CHRM1DRD2OPRM1PLD2PLD1 | |
| Hydrochloric Acid SCHEMBL30899388 | 0.85 | CHRM1 (0.58) | CHRM1DRD2OPRM1PLD2PLD1 | |
| SCHEMBL11592859 | 0.85 | CHRM1 (0.54) | CHRM1DRD2OPRM1PLD2PLD1 | |
| SCHEMBL1152107 | 0.84 | CHRM1 (0.64) | CHRM1DRD2OPRM1PLD2PLD1 | |
| SCHEMBL11594258 | 0.83 | OPRM1 (0.52) | CHRM1DRD2OPRM1CHRM2CHRM4 | |
| SCHEMBL11593726 | 0.83 | CHRM1 (0.46) | CHRM1DRD2OPRM1PLD2PLD1 | |
| SCHEMBL11594089 | 0.82 | CHRM1 (0.57) | CHRM1DRD2OPRM1PLD2PLD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4076821-A | 4,4-Diphenylcycloalkylpiperidines and psychotropic compositions thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JA) | 1978-02-28 | — | — | US | disclosed |