Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.78 |
| ▸ | TSHR | P16473 | 4/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 7/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11595412 | 0.88 | SMN1; SMN2 (0.62) | SMN1; SMN2KMT2ATSHRCYP1A2CYP2C19 | |
| SCHEMBL11597649 | 0.88 | SMN1; SMN2 (1.00) | SMN1; SMN2KMT2ATSHRCYP1A2CYP2C19 | |
| SCHEMBL11596505 | 0.87 | SMN1; SMN2 (0.60) | SMN1; SMN2KMT2ATSHRCYP1A2CYP2C19 | |
| SCHEMBL11597512 | 0.85 | SMN1; SMN2 (0.74) | SMN1; SMN2KMT2ATSHRCYP1A2CYP2C19 | |
| SCHEMBL11207114 | 0.84 | SMN1; SMN2 (0.72) | SMN1; SMN2KMT2ATSHRCYP1A2CYP2C19 | |
| SCHEMBL11596069 | 0.83 | SMN1; SMN2 (0.54) | SMN1; SMN2KMT2ATSHRCYP1A2CYP2C19 | |
| SCHEMBL11595506 | 0.80 | SMN1; SMN2 (0.66) | SMN1; SMN2KMT2ATSHRCYP1A2CYP2C19 | |
| SCHEMBL198040 | 0.79 | SMN1; SMN2 (0.65) | SMN1; SMN2KMT2ATSHRCYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL9194133 | 0.78 | SMN1; SMN2 (0.63) | SMN1; SMN2KMT2ATSHRCYP1A2CYP2C19 | |
| SCHEMBL11151096 | 0.78 | ALDH1A1 (0.67) | SMN1; SMN2KMT2ATSHRCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4125614-A | DIURETIC | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-11-14 | — | — | US | disclosed |
| US-4061761-A | Thiazolidine derivatives | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-12-06 | — | — | US | disclosed |