Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 10/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.47 |
| ▸ | DRD2 | P14416 | 4/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | PLD2 | O14939 | 4/20 | 0.47 |
| ▸ | PLD1 | Q13393 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11593231 | 0.99 | CHRM1 (0.47) | CHRM1OPRM1DRD2HTR1AADRA2A | |
| SCHEMBL1153304 | 0.94 | CHRM1 (0.50) | CHRM1OPRM1DRD2HTR1AHTR2A | |
| SCHEMBL11593459 | 0.89 | DRD2 (0.51) | CHRM1OPRM1DRD2HTR1AADRA2A | |
| SCHEMBL11593000 | 0.83 | CHRM1 (0.56) | CHRM1OPRM1DRD2HTR1AADRA2A | |
| SCHEMBL1153122 | 0.83 | CHRM1 (0.52) | CHRM1OPRM1DRD2HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL11592168 | 0.82 | CHRM1 (0.55) | CHRM1OPRM1DRD2HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL1152327 | 0.82 | CHRM1 (0.51) | CHRM1OPRM1DRD2HTR1AHTR2A | |
| SCHEMBL11595899 | 0.81 | DRD2 (0.52) | CHRM1OPRM1DRD2HTR1AADRA2A | |
| SCHEMBL11593726 | 0.77 | CHRM1 (0.46) | CHRM1OPRM1DRD2PLD2PLD1 | |
| SCHEMBL11594238 | 0.76 | CHRM1 (0.59) | CHRM1OPRM1DRD2PLD2PLD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4076821-A | 4,4-Diphenylcycloalkylpiperidines and psychotropic compositions thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JA) | 1978-02-28 | — | — | US | claimed |