Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.49 |
| ▸ | PI4KA | P42356 | 1/20 | 0.49 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.49 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.49 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.49 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 5/20 | 0.41 |
| ▸ | CDK1 | P06493 | 5/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 5/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | ADA | P00813 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31331738 | 0.87 | ADORA2A (0.64) | ADORA2AADORA2BADORA1PI4KAPI4K2B | |
| SCHEMBL2475932 | 0.87 | ADORA2A (0.64) | ADORA2AADORA2BADORA1PI4KAPI4K2B | |
| SCHEMBL21539218 | 0.84 | ADORA2A (0.51) | ADORA2AADORA2BADORA1PI4KAPI4K2B | |
| SCHEMBL11258096 | 0.84 | ADORA2A (0.47) | ADORA2AADORA2BADORA1PI4KAPI4K2B | |
| SCHEMBL248370 | 0.83 | ADORA2A (0.44) | ADORA2AADORA2BADORA1PI4KAPI4K2B | |
| SCHEMBL11595833 | 0.81 | ADORA2A (0.45) | ADORA2AADORA2BADORA1PI4KAPI4K2B | |
| SCHEMBL11596964 | 0.81 | ADORA2A (0.45) | ADORA2AADORA2BADORA1PI4KAPI4K2B | |
| SCHEMBL11596855 | 0.81 | ADORA2A (0.51) | ADORA2AADORA2BADORA1PI4KAPI4K2B | |
| SCHEMBL5016844 | 0.81 | ADORA2A (0.75) | ADORA2AADORA2BADORA1PI4KAPI4K2B | |
| SCHEMBL11596724 | 0.80 | ADORA2A (0.50) | ADORA2AADORA2BADORA1PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4100286-A | 2-(Substituted heterocyclic amine)benzoic acids | SCIENCE UNION ET CIE (FR) | 1978-07-11 | — | — | US | disclosed |