SCHEMBL11596603

SCHEMBL11596603

NC(=O)CSC(=S)OCC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP1A2 P05177 1/20 0.36
TSHR P16473 1/20 0.34
CTH P32929 1/20 0.34
CBS P35520 1/20 0.34
THPO P40225 1/20 0.34
CYP2C19 P33261 1/20 0.34
THRB P10828 1/20 0.33
HDAC3 O15379 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC7 Q8WUI4 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC10 Q969S8 1/20 0.31
HDAC11 Q96DB2 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
HDAC9 Q9UKV0 1/20 0.31
HDAC5 Q9UQL6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31070065 0.85 CYP2D6 (0.67) ALDH1A1CYP2D6CYP1A2TSHRCTH
SCHEMBL10639419 0.84 CYP2D6 (0.60) ALDH1A1CYP2D6CYP1A2TSHRCTH
SCHEMBL3416817 0.78 ALDH1A1 (0.68) ALDH1A1CYP2D6CYP1A2HDAC3HDAC4
SCHEMBL13592487 0.72
SCHEMBL9838494 0.71
SCHEMBL9937835 0.71
SCHEMBL9938562 0.69 TSHR (0.43) ALDH1A1CYP2D6CYP1A2TSHRCTH
SCHEMBL10521802 0.67 TSHR (0.42) ALDH1A1CYP2D6CYP1A2TSHRCTH
SCHEMBL3412115 0.67 ALDH1A1 (1.00) ALDH1A1CYP2D6CYP2C19HDAC3HDAC4
SCHEMBL10708063 0.67 CYP2D6 (0.53) ALDH1A1CYP2D6CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4080207-A Radiation-sensitive compositions and photographic elements containing N-(acylhydrazinophenyl) thioamide nucleating agents EASTMAN KODAK COMPANY (US) 1978-03-21 US disclosed