Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.69 |
| ▸ | RAB9A | P51151 | 3/20 | 0.69 |
| ▸ | HTT | P42858 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | CA12 | O43570 | 3/20 | 0.59 |
| ▸ | CA2 | P00918 | 3/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | APP | P05067 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11593766 | 0.89 | MAPT (0.81) | MAPTRAB9AHTTMEN1KMT2A | |
| SCHEMBL27769271 | 0.86 | MAPT (0.68) | MAPTRAB9AHTTMEN1KMT2A | |
| SCHEMBL10781073 | 0.83 | MAPT (0.73) | MAPTRAB9AHTTMEN1KMT2A | |
| SCHEMBL30208389 | 0.83 | HIF1A (0.74) | MAPTRAB9AHTTMEN1KMT2A | |
| SCHEMBL802584 | 0.83 | HIF1A (0.74) | MAPTRAB9AHTTMEN1KMT2A | |
| SCHEMBL28911913 | 0.81 | HIF1A (0.72) | MAPTRAB9AHTTMEN1KMT2A | |
| Bromide SCHEMBL27616592 | 0.81 | HIF1A (0.72) | MAPTRAB9AHTTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11833104 | 0.81 | HIF1A (0.72) | MAPTRAB9AHTTMEN1KMT2A | |
| SCHEMBL11594145 | 0.80 | MAPT (0.69) | MAPTRAB9AHTTMEN1KMT2A | |
| SCHEMBL802037 | 0.80 | MAPT (1.00) | MAPTRAB9AHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4129556-A | N,N'-BIS-(2-HYDROXYBENZYL)-ALKYLENE-DIAMINES, N,N'-BIS-(2-HYDROXYBENZYL)-ARYLENE-DIAMINES | CIBA-GEIGY CORPORATION (US) | 1978-12-12 | — | — | US | disclosed |