Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 10/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11606669 | 0.90 | KMT2A (0.51) | GRM5MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL11613075 | 0.88 | KMT2A (0.50) | GRM5MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL11597962 | 0.80 | GRM5 (0.45) | GRM5 | |
| SCHEMBL9595952 | 0.77 | KMT2A (0.42) | GRM5RAB9AMAPTNPC1ALDH1A1 | |
| SCHEMBL11597389 | 0.77 | NPC1 (0.57) | GRM5RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13296220 | 0.75 | GRM5 (0.82) | GRM5RAB9AMAPTNPC1HSD17B10 | |
| SCHEMBL9829998 | 0.74 | GRM5 (0.44) | GRM5RAB9AMAPTNPC1ALDH1A1 | |
| SCHEMBL3860067 | 0.73 | GRM5 (1.00) | GRM5RAB9AMAPTNPC1HPGD | |
| SCHEMBL9603380 | 0.73 | KMT2A (0.42) | GRM5RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9832511 | 0.73 | CDK5 (0.55) | GRM5RAB9AMAPTNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4112101-A | N-(Pyridyl)-1H-(or 2H) tetrazole-5-carboxamide derivatives for the prevention of immediate type hypersensitivity reactions | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-09-05 | — | — | US | claimed |
| US-4112101-A | N-(Pyridyl)-1H-(or 2H) tetrazole-5-carboxamide derivatives for the prevention of immediate type hypersensitivity reactions | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-09-05 | — | — | US | disclosed |