Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 3/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9603380 | 0.84 | KMT2A (0.42) | KMT2ARAB9AMEN1NPC1ATM | |
| SCHEMBL11596891 | 0.77 | GRM5 (0.57) | RAB9ANPC1SMN1; SMN2ALDH1A1GRM5 | |
| SCHEMBL9603546 | 0.77 | KMT2A (0.41) | KMT2ARAB9AMEN1NPC1ATM | |
| SCHEMBL23183075 | 0.66 | RAB9A (0.63) | KMT2ARAB9AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL11606669 | 0.66 | KMT2A (0.51) | KMT2AMEN1ALDH1A1GRM5MAPT | |
| SCHEMBL11613075 | 0.65 | KMT2A (0.50) | KMT2AMEN1ALDH1A1GRM5MAPT | |
| SCHEMBL8998970 | 0.64 | ESR1 (0.39) | KMT2ARAB9AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL8998974 | 0.64 | ESR1 (0.39) | KMT2ARAB9AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL9588376 | 0.64 | KMT2A (0.52) | KMT2ARAB9AMEN1NPC1ATM | |
| SCHEMBL6663529 | 0.64 | RAB9A (0.66) | KMT2ARAB9AMEN1NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016076-A1 | 3-(1H^_-TETRAZOL-5-YL)-4H^_-PYRIDO[1,2-A^_]PYRIMIDINE-4-ONES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND THE PREPARATION THEREOF | CHINOIN GYÓGYSZER- ÉS VEGYÉSZETI TERMÉKEK GYÁRA RT. (HU) | 1993-08-19 | — | — | WO | disclosed |
| WO-1993016070-A1 | 3-(PYRIDYLAMINO)-2-(1H^_-TETRAZOL-5-YL)-ACRYLNITRILES AND A PROCESS FOR THE PREPARATION THEREOF | CHINOIN GYÓGYSZER- ÉS VEGYÉSZETI TERMÉKEK GYÁRA RT. (HU) | 1993-08-19 | — | — | WO | disclosed |