Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.51 |
| ▸ | PPARG | P37231 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11598248 | 0.97 | PPARA (0.47) | PPARAPPARGMEN1KMT2AKDM4E | |
| SCHEMBL11595888 | 0.86 | PPARA (0.54) | PPARAPPARGMEN1KMT2AKDM4E | |
| SCHEMBL11597072 | 0.83 | PPARA (0.50) | PPARAPPARGMEN1KMT2AKDM4E | |
| SCHEMBL11595598 | 0.83 | PPARA (0.55) | PPARAPPARGMEN1KMT2AKDM4E | |
| SCHEMBL11596932 | 0.81 | PPARA (0.52) | PPARAPPARGMEN1KMT2AALDH1A1 | |
| SCHEMBL11598113 | 0.80 | PPARA (0.55) | PPARAPPARGMEN1KMT2AKDM4E | |
| SCHEMBL11596113 | 0.79 | PPARA (0.51) | PPARAPPARGMEN1KMT2AKDM4E | |
| SCHEMBL11598654 | 0.79 | PPARA (0.48) | PPARAPPARGMEN1KMT2AKDM4E | |
| SCHEMBL11597711 | 0.78 | PPARG (0.52) | PPARAPPARGMEN1KMT2APPARD | |
| SCHEMBL11597008 | 0.77 | KDM4E (0.48) | PPARAPPARGKDM4EPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4125732-A | HYPOLIPIDEMIC | AMERICAN CYANAMID COMPANY (US) | 1978-11-14 | — | — | US | disclosed |