Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | ABAT | P80404 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.41 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | GRK2 | P25098 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL11667677 | 0.85 | ABAT (0.47) | PKMABATLMNAMEN1MAPT | |
| Allylamine SCHEMBL11049347 | 0.85 | PKM (0.34) | PKMTGM2ABATLMNAMEN1 | |
| Ethylene SCHEMBL8097301 | 0.85 | ABAT (0.50) | PKMABATLMNAMEN1MAPT | |
| Hydrazine SCHEMBL2403240 | 0.85 | ABAT (0.50) | PKMABATLMNAMEN1MAPT | |
| Hydrochloric Acid SCHEMBL3069393 | 0.84 | ABAT (0.53) | PKMABATLMNAMEN1MAPT | |
| SCHEMBL7785939 | 0.84 | ABAT (0.53) | PKMABATLMNAMEN1MAPT | |
| Benzene SCHEMBL27714747 | 0.84 | ABAT (0.53) | PKMABATLMNAMEN1MAPT | |
| SCHEMBL1330698 | 0.84 | ABAT (0.53) | PKMABATLMNAMEN1MAPT | |
| SCHEMBL41828 | 0.84 | ABAT (0.53) | PKMABATLMNAMEN1MAPT | |
| Hydrochloric Acid SCHEMBL2006870 | 0.84 | ABAT (0.53) | PKMABATLMNAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4091227-A | ANTIBACTERIAL AGENTS | SMITHKLINE CORPORATION (US) | 1978-05-23 | — | — | US | disclosed |
| US-4067978-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-4067977-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-4067976-A | BACTERICIDES | SMITHKLINE CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-4007173-A | BACTERICIDE | SMITHKLINE CORPORATION (US) | 1977-02-08 | — | — | US | disclosed |