Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.54 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PAM | P19021 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11598259 | 0.97 | DGKA (0.58) | DGKADNM1ADRA2AADRA1AMAPT | |
| SCHEMBL11601599 | 0.97 | DGKA (0.58) | DGKADNM1ADRA2AADRA1AMAPT | |
| SCHEMBL11599018 | 0.95 | DGKA (0.48) | DGKADNM1ADRA2AADRA1AMAPT | |
| SCHEMBL11601881 | 0.90 | DGKA (0.54) | DGKADNM1ADRA2AADRA1AMAPT | |
| SCHEMBL11791792 | 0.89 | DGKA (0.73) | DGKADNM1MAPTPAMPRSS1 | |
| SCHEMBL11599030 | 0.87 | DGKA (0.52) | DGKADNM1ADRA2AADRA1AMAPT | |
| SCHEMBL11599108 | 0.87 | DGKA (0.58) | DGKADNM1ADRA2AADRA1AMAPT | |
| SCHEMBL1693910 | 0.87 | DGKA (0.64) | DGKADNM1ADRA2AADRA1AMAPT | |
| SCHEMBL31721561 | 0.87 | DGKA (0.64) | DGKADNM1ADRA2AADRA1AMAPT | |
| SCHEMBL8446335 | 0.87 | DGKA (0.77) | DGKADNM1MAPTPAMPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4104233-A | VINYL HALIDE POLYMERS, SMOKE AND FIRE RETARDANTS | MONSANTO COMPANY (US) | 1978-08-01 | — | — | US | claimed |
| US-4104233-A | VINYL HALIDE POLYMERS, SMOKE AND FIRE RETARDANTS | MONSANTO COMPANY (US) | 1978-08-01 | — | — | US | disclosed |