Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 6/20 | 0.48 |
| ▸ | PPARG | P37231 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6267772 | 1.00 | GBA1 (0.48) | GBA1PPARGTSHRTP53CYP3A4 | |
| SCHEMBL11787564 | 1.00 | GBA1 (0.48) | GBA1PPARGTSHRTP53CYP3A4 | |
| SCHEMBL7165503 | 0.86 | GBA1 (0.47) | GBA1PPARGTSHRTP53CYP3A4 | |
| SCHEMBL15188961 | 0.78 | GBA1 (0.40) | GBA1PPARGTSHRALDH1A1TDP1 | |
| SCHEMBL10334445 | 0.71 | — | — | |
| SCHEMBL6524160 | 0.70 | GBA1 (0.47) | GBA1TSHRTP53CYP3A4MAPK1 | |
| SCHEMBL6517051 | 0.68 | GBA1 (0.50) | GBA1TSHRMAPK1ALDH1A1LMNA | |
| SCHEMBL6519035 | 0.68 | GBA1 (0.50) | GBA1TSHRMAPK1ALDH1A1LMNA | |
| SCHEMBL6519598 | 0.68 | GBA1 (0.50) | GBA1TSHRMAPK1ALDH1A1LMNA | |
| SCHEMBL6520331 | 0.68 | GBA1 (0.50) | GBA1TSHRMAPK1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4132726-A | INTERMEDIATES FOR PROSTAGLANDIN COMPOUNDS | TEIJIN LIMITED (JP) | 1979-01-02 | — | — | US | disclosed |
| US-4008125-A | New cyclopentene-diols and new acyl esters thereof and process for their preparation | TEIJIN LIMITED (JA) | 1977-02-15 | — | — | US | disclosed |