Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11787564 | 0.86 | GBA1 (0.48) | GBA1ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL11599116 | 0.86 | GBA1 (0.48) | GBA1ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL6267772 | 0.86 | GBA1 (0.48) | GBA1ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL6524160 | 0.77 | GBA1 (0.47) | GBA1ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL7116764 | 0.77 | MAPK1 (0.35) | GBA1ALDH1A1TSHRMAPK1TP53 | |
| SCHEMBL7116761 | 0.77 | MAPK1 (0.35) | GBA1ALDH1A1TSHRMAPK1TP53 | |
| SCHEMBL7116766 | 0.77 | MAPK1 (0.35) | GBA1ALDH1A1TSHRMAPK1TP53 | |
| SCHEMBL6517051 | 0.76 | GBA1 (0.50) | GBA1ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL6519035 | 0.76 | GBA1 (0.50) | GBA1ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL6519598 | 0.76 | GBA1 (0.50) | GBA1ALDH1A1TDP1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915073-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ISOMERS OF TRICYCLIC COMPOUNDS | TORAY INDUSTRIES (JP) | 2003-08-13 | — | — | EP | claimed |
| US-6103914-A | Method of producing optically active material of tricyclic compound | TORAY INDUSTRIES, INC. (JP) | 2000-08-15 | — | — | US | claimed |
| EP-0915073-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ISOMERS OF TRICYCLIC COMPOUNDS | TORAY INDUSTRIES, INC. (JP) | 1999-05-12 | — | — | EP | claimed |
| EP-0915073-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ISOMERS OF TRICYCLIC COMPOUNDS | TORAY INDUSTRIES (JP) | 2003-08-13 | — | — | EP | disclosed |
| US-6103914-A | Method of producing optically active material of tricyclic compound | TORAY INDUSTRIES, INC. (JP) | 2000-08-15 | — | — | US | disclosed |
| EP-0915073-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ISOMERS OF TRICYCLIC COMPOUNDS | TORAY INDUSTRIES, INC. (JP) | 1999-05-12 | — | — | EP | disclosed |