Methane

Methane

SCHEMBL11599142

C.O=C=NC(N=C=O)(c1ccccc1)c1ccccc1

nearest known ligand 0.35

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Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 4/20 0.35
TSHR P16473 2/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP1A2 P05177 1/20 0.33
PTPN1 P18031 1/20 0.32
CA2 P00918 2/20 0.32
CA5A P35218 2/20 0.32
CA4 P22748 1/20 0.32
CA1 P00915 1/20 0.31
CA9 Q16790 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
MAPK1 P28482 1/20 0.31
CYP2C19 P33261 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15413 0.98 KCNN4 (0.36) KCNN4TSHRALDH1A1CYP1A2PTPN1
SCHEMBL1149592 0.98 KCNN4 (0.36) KCNN4TSHRALDH1A1CYP1A2PTPN1
SCHEMBL2476985 0.95 KCNN4 (0.35) KCNN4TSHRALDH1A1CYP1A2PTPN1
SCHEMBL8578358 0.95 KCNN4 (0.35) KCNN4TSHRALDH1A1CYP1A2PTPN1
SCHEMBL28448472 0.95 KCNN4 (0.35) KCNN4TSHRALDH1A1CYP1A2PTPN1
Water SCHEMBL10334361 0.95 KCNN4 (0.35) KCNN4TSHRALDH1A1CYP1A2PTPN1
SCHEMBL19128956 0.95 KCNN4 (0.35) KCNN4TSHRALDH1A1CYP1A2PTPN1
Water SCHEMBL2069627 0.95 KCNN4 (0.35) KCNN4TSHRALDH1A1CYP1A2PTPN1
SCHEMBL28385259 0.95 KCNN4 (0.35) KCNN4TSHRALDH1A1CYP1A2PTPN1
Carbimide SCHEMBL9278669 0.91 TSHR (0.32) KCNN4TSHRALDH1A1CYP1A2PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4067931-A POLYURETHANE FOAMS UNIROYAL, INC. (US) 1978-01-10 US disclosed