Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 6/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA5A | P35218 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15413 | 0.98 | KCNN4 (0.36) | KCNN4TSHRALDH1A1CYP1A2PTPN1 | |
| SCHEMBL1149592 | 0.98 | KCNN4 (0.36) | KCNN4TSHRALDH1A1CYP1A2PTPN1 | |
| SCHEMBL28385259 | 0.95 | KCNN4 (0.35) | KCNN4TSHRALDH1A1CYP1A2PTPN1 | |
| Methane SCHEMBL11599142 | 0.95 | KCNN4 (0.35) | KCNN4TSHRALDH1A1CYP1A2PTPN1 | |
| Water SCHEMBL10334361 | 0.95 | KCNN4 (0.35) | KCNN4TSHRALDH1A1CYP1A2PTPN1 | |
| SCHEMBL19128956 | 0.95 | KCNN4 (0.35) | KCNN4TSHRALDH1A1CYP1A2PTPN1 | |
| Water SCHEMBL2069627 | 0.95 | KCNN4 (0.35) | KCNN4TSHRALDH1A1CYP1A2PTPN1 | |
| SCHEMBL8578358 | 0.95 | KCNN4 (0.35) | KCNN4TSHRALDH1A1CYP1A2PTPN1 | |
| SCHEMBL28448472 | 0.95 | KCNN4 (0.35) | KCNN4TSHRALDH1A1CYP1A2PTPN1 | |
| SCHEMBL5961207 | 0.92 | KCNN4 (0.31) | KCNN4TSHRALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1964866-B1 | Manufacture of hard polyurethane elastomer moulded articles | BASF SE (DE) | 2011-09-07 | — | — | EP | claimed |
| CN-100429255-C | Method for producing rigid foams from alkaline polyether polyols | BAYER MATERIALSCIENCE LLC (US) | 2008-10-29 | — | — | CN | claimed |
| US-20080262168-A1 | Reacting a polyisocyanate and reactive material in presence of trimerization catalysts; polyisocyanate containing diphenylmethane diisocyanate; reacting with polyether; forming polyetherurethane copolymer | HUNTSMAN INTERNATIONAL LLC (US) | 2008-10-23 | — | — | US | claimed |
| US-20080227929-A1 | Process for Preparing a Polyisocyanurate Polyurethane Material | HUNTSMAN INTERNATIONAL LLC (US) | 2008-09-18 | — | — | US | claimed |
| EP-1964866-A2 | Manufacture of hard polyurethane elastomer moulded articles | BASF SE (DE) | 2008-09-03 | — | — | EP | claimed |
| CN-1768088-A | A process for the production of rigid foams from alkaline polyether polyols | BAYER MATERIALSCIENCE LLC (US) | 2006-05-03 | — | — | CN | claimed |
| EP-1053268-B1 | ELASTOMERS FROM COMPOSITIONS COMPRISING RIGID THERMOPLASTIC POLYURETHANE | HUNTSMAN INT LLC (US) | 2002-10-02 | — | — | EP | claimed |
| CN-100429255-C | Method for producing rigid foams from alkaline polyether polyols | BAYER MATERIALSCIENCE LLC (US) | 2008-10-29 | — | — | CN | disclosed |
| CN-1768088-A | A process for the production of rigid foams from alkaline polyether polyols | BAYER MATERIALSCIENCE LLC (US) | 2006-05-03 | — | — | CN | disclosed |