Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8516393 | 0.90 | — | — | |
| SCHEMBL28324778 | 0.85 | ALDH1A1 (0.41) | ALDH1A1BCHEPOLBMAOAACHE | |
| SCHEMBL26091 | 0.80 | — | — | |
| SCHEMBL30996263 | 0.70 | — | — | |
| SCHEMBL6204608 | 0.68 | — | — | |
| SCHEMBL7106016 | 0.68 | — | — | |
| SCHEMBL4613888 | 0.68 | AURKA (0.31) | — | |
| SCHEMBL5485107 | 0.67 | — | — | |
| SCHEMBL9937744 | 0.63 | — | — | |
| SCHEMBL30955040 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4077983-A | PROGESTATIONAL ACTIVITY | HOFFMANN-LA ROCHE, INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4061679-A | Stereospecific total steroidal synthesis via substituted C/D-trans indanones | HOFFMANN-LA ROCHE INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4059612-A | Substituted indanones | HOFFMANN-LA ROCHE, INC. (US) | 1977-11-22 | — | — | US | disclosed |
| US-4053486-A | STEREOSPECIFIC TOTAL STEROIDAL SYNTHESIS VIA SUBSTITUTED C/D-TRANS INDANONES | HOFFMANN-LA ROCHE INC. (US) | 1977-10-11 | — | — | US | disclosed |
| US-4052413-A | STEREOSPECIFIC TOTAL STEROIDAL SYNTHESIS VIA SUBSTITUTED C/D-TRANS INDANONES | HOFFMANN-LA ROCHE, INC. (US) | 1977-10-04 | — | — | US | disclosed |
| US-4049677-A | Stereospecific total steroidal synthesis via substituted C/D-trans indanones | HOFFMAN-LA ROCHE INC. (US) | 1977-09-20 | — | — | US | disclosed |
| US-4048195-A | Process of synthesizing substituted indanones | HOFFMANN-LA ROCHE INC. (US) | 1977-09-13 | — | — | US | disclosed |
| US-3985733-A | Stereospecific total steroidal synthesis via substituted C/D-trans indanones | HOFFMANN-LA ROCHE INC. (US) | 1976-10-12 | — | — | US | disclosed |
| US-3984473-A | Stereospecific total steroidal synthesis via substituted C/D-trans indanones | HOFFMANN-LA ROCHE INC. (US) | 1976-10-05 | — | — | US | disclosed |
| US-3965117-A | Stereospecific total steroidal synthesis via substituted c/d-trans indanones | HOFFMANN-LA ROCHE INC. (US) | 1976-06-22 | — | — | US | disclosed |
| US-3950389-A | Stereospecific total steroidal synthesis via substituted C/D-trans indanones | HOFFMANN-LA ROCHE INC. (US) | 1976-04-13 | — | — | US | disclosed |