Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11600345 | 0.91 | MEN1 (0.60) | MAPTALDH1A1HTTALOX12L3MBTL1 | |
| SCHEMBL11600667 | 0.89 | MEN1 (0.58) | MAPTALDH1A1HTTCYP1A2CYP3A4 | |
| SCHEMBL1931351 | 0.89 | MEN1 (0.66) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL3889607 | 0.81 | NPC1 (0.66) | ALDH1A1CYP3A4MEN1KMT2ANPC1 | |
| SCHEMBL5122923 | 0.79 | ALDH1A1 (0.80) | MAPTALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL10055053 | 0.79 | ALDH1A1 (0.57) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL5391138 | 0.79 | ALDH1A1 (0.62) | MAPTALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL31396093 | 0.76 | MAPT (0.75) | MAPTALDH1A1HTTCYP1A2CYP3A4 | |
| SCHEMBL6405773 | 0.74 | ALDH1A1 (1.00) | MAPTALDH1A1HTTCYP1A2CYP3A4 | |
| SCHEMBL13644737 | 0.74 | ALDH1A1 (1.00) | MAPTALDH1A1HTTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4124565-A | STABILIZERS, ANTIOXIDANTS, ANTIOZONANTS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-11-07 | — | — | US | disclosed |