Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 14/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11599596 | 0.81 | BRD4 (0.63) | ALDH1A1PKMKDM4EBRD4SMN1; SMN2 | |
| SCHEMBL9290447 | 0.75 | BRD4 (0.55) | ALDH1A1PKMBRD4SMN1; SMN2MEN1 | |
| SCHEMBL11601731 | 0.73 | BRD4 (0.62) | ALDH1A1PKMKDM4EBRD4SMN1; SMN2 | |
| SCHEMBL11665172 | 0.69 | BRD4 (0.47) | ALDH1A1PKMBRD4SMN1; SMN2MEN1 | |
| SCHEMBL11599528 | 0.69 | BRD4 (0.64) | ALDH1A1PKMKDM4EBRD4SMN1; SMN2 | |
| SCHEMBL12235840 | 0.69 | HPGD (0.62) | ALDH1A1PKMSMN1; SMN2MEN1MAPT | |
| SCHEMBL20864175 | 0.69 | POLB (0.72) | ALDH1A1KDM4ESMN1; SMN2MEN1MAPT | |
| SCHEMBL25520362 | 0.68 | MEN1 (0.56) | ALDH1A1PKMKDM4EBRD4SMN1; SMN2 | |
| SCHEMBL11601545 | 0.67 | BRD4 (0.56) | ALDH1A1PKMKDM4EBRD4SMN1; SMN2 | |
| SCHEMBL11213051 | 0.67 | BRD4 (0.65) | ALDH1A1PKMKDM4EBRD4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE29834-E | PREPARED FROM 4-SULFONYL-1,8-NAPHTHOLACTAMS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-11-14 | — | — | US | disclosed |
| US-3959310-A | BENZINDOLE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-25 | — | — | US | disclosed |