Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 15/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | PKM | P14618 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | RORC | P51449 | 3/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11601731 | 0.90 | BRD4 (0.62) | BRD4ALDH1A1PKMSMN1; SMN2MEN1 | |
| SCHEMBL11599528 | 0.86 | BRD4 (0.64) | BRD4ALDH1A1PKMSMN1; SMN2MEN1 | |
| SCHEMBL11213051 | 0.84 | BRD4 (0.65) | BRD4ALDH1A1PKMSMN1; SMN2MEN1 | |
| SCHEMBL11601545 | 0.84 | BRD4 (0.56) | BRD4ALDH1A1PKMSMN1; SMN2MEN1 | |
| SCHEMBL11601951 | 0.83 | BRD4 (0.67) | BRD4ALDH1A1PKMSMN1; SMN2MEN1 | |
| SCHEMBL9290447 | 0.83 | BRD4 (0.55) | BRD4ALDH1A1PKMSMN1; SMN2MEN1 | |
| SCHEMBL11599450 | 0.81 | ALDH1A1 (0.47) | BRD4ALDH1A1PKMSMN1; SMN2MEN1 | |
| SCHEMBL9450615 | 0.79 | BRD4 (0.73) | BRD4ALDH1A1PKMSMN1; SMN2MEN1 | |
| SCHEMBL11600211 | 0.79 | BRD4 (0.64) | BRD4ALDH1A1PKMSMN1; SMN2MEN1 | |
| SCHEMBL11601461 | 0.78 | BRD4 (0.58) | BRD4ALDH1A1PKMSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE29834-E | PREPARED FROM 4-SULFONYL-1,8-NAPHTHOLACTAMS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-11-14 | — | — | US | disclosed |
| US-3959310-A | BENZINDOLE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-25 | — | — | US | disclosed |