Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 8/20 | 0.84 |
| ▸ | CCR1 | P32246 | 6/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.58 |
| ▸ | DRD3 | P35462 | 2/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.58 |
| ▸ | CCR3 | P51677 | 2/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.54 |
| ▸ | HTR1A | P08908 | 2/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11625051 | 0.92 | KCNA3 (1.00) | KCNA3CCR1RAB9ANPSR1OPRM1 | |
| Hydrochloric Acid SCHEMBL11628063 | 0.89 | KCNA3 (0.94) | KCNA3CCR1RAB9ANPSR1OPRM1 | |
| SCHEMBL2312804 | 0.80 | CCR1 (1.00) | KCNA3CCR1OPRM1CCR3 | |
| Hydrochloric Acid SCHEMBL11629523 | 0.79 | CCR1 (0.98) | KCNA3CCR1OPRM1CCR3 | |
| SCHEMBL30659491 | 0.79 | KCNA3 (0.75) | KCNA3CCR1RAB9ANPSR1OPRM1 | |
| SCHEMBL11616292 | 0.78 | KCNA3 (0.73) | KCNA3CCR1RAB9ANPSR1OPRM1 | |
| Hydrochloric Acid SCHEMBL9244847 | 0.78 | KCNA3 (0.97) | KCNA3CCR1RAB9ANPSR1OPRM1 | |
| SCHEMBL10461573 | 0.76 | KCNA3 (0.71) | KCNA3RAB9ANPSR1OPRM1DRD3 | |
| SCHEMBL5591855 | 0.76 | ALDH1A1 (0.60) | KCNA3OPRM1DRD3DRD4CCR3 | |
| Hydrochloric Acid SCHEMBL10920910 | 0.76 | KCNA3 (0.70) | KCNA3RAB9ANPSR1OPRM1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE29556-E | 1,1-Diaryl-1-oxadiazol-alkylamines | G. D. SEARLE & CO. (US) | 1978-02-28 | — | — | US | disclosed |
| US-4017491-A | 1,1-Diaryl-1H-tetrazole amines | G. D. SEARLE & CO. (US) | 1977-04-12 | — | — | US | disclosed |