Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3426497 | 0.81 | OPRM1 (0.36) | OPRM1OPRD1OPRK1 | |
| SCHEMBL3428870 | 0.79 | KDM4E (0.39) | OPRM1OPRD1OPRK1 | |
| SCHEMBL11598263 | 0.76 | PLG (0.36) | OPRM1OPRD1OPRK1 | |
| SCHEMBL21359084 | 0.75 | OPRM1 (0.42) | OPRM1OPRD1OPRK1 | |
| SCHEMBL3429248 | 0.73 | OPRM1 (0.42) | OPRM1OPRD1OPRK1 | |
| SCHEMBL1414182 | 0.70 | ESR2 (0.38) | — | |
| SCHEMBL8056724 | 0.69 | ESR1 (0.34) | — | |
| SCHEMBL9457916 | 0.69 | ESR1 (0.34) | — | |
| SCHEMBL3426492 | 0.68 | OPRM1 (0.33) | OPRM1OPRD1OPRK1 | |
| SCHEMBL12443378 | 0.67 | KDM4E (0.40) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4070400-A | MICROBIOCIDES, ALGICIDES | MERCK & CO., INC. (US) | 1978-01-24 | — | — | US | disclosed |
| US-4060639-A | Broad spectrum antibacterial compositions containing tris-(hydroxymethyl)-aminoethane and dicycloaliphatic-alkyl polyamines | MERCK & CO., INC. (US) | 1977-11-29 | — | — | US | disclosed |
| US-4049417-A | CONTAINING CYCLOHEXYL OR CYCLOHEXENYL RINGS | MERCK & CO., INC. (US) | 1977-09-20 | — | — | US | disclosed |
| US-4035174-A | MICROBIOCIDES | MERCK & CO., INC. (US) | 1977-07-12 | — | — | US | disclosed |