Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 10/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | CCR3 | P51677 | 2/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | CCR1 | P32246 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11626788 | 0.92 | KCNA3 (0.57) | KCNA3RAB9ANPSR1CCR3OPRM1 | |
| Hydrochloric Acid SCHEMBL11627731 | 0.90 | CCR3 (0.62) | KCNA3RAB9ANPSR1CCR3CCR1 | |
| SCHEMBL11600548 | 0.86 | KCNA3 (0.51) | KCNA3RAB9ANPSR1CCR3OPRM1 | |
| SCHEMBL11601553 | 0.85 | KCNA3 (0.65) | KCNA3RAB9ANPSR1CCR3OPRM1 | |
| SCHEMBL11598658 | 0.84 | KCNA3 (0.54) | KCNA3RAB9ANPSR1CCR3OPRM1 | |
| Hydrochloric Acid SCHEMBL11627511 | 0.83 | KCNA3 (0.53) | KCNA3RAB9ANPSR1CCR3OPRM1 | |
| SCHEMBL11731812 | 0.81 | CCR1 (0.59) | KCNA3CCR3CCR1 | |
| SCHEMBL11729635 | 0.79 | CCR1 (0.53) | KCNA3CCR3CCR1 | |
| SCHEMBL11712812 | 0.78 | KCNA3 (1.00) | KCNA3RAB9ANPSR1CCR3OPRM1 | |
| Hydrochloric Acid SCHEMBL11625263 | 0.78 | KCNA3 (0.97) | KCNA3RAB9ANPSR1CCR3OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE29556-E | 1,1-Diaryl-1-oxadiazol-alkylamines | G. D. SEARLE & CO. (US) | 1978-02-28 | — | — | US | disclosed |