Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 9/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CCR1 | P32246 | 2/20 | 0.45 |
| ▸ | CCR3 | P51677 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11729635 | 0.93 | CCR1 (0.53) | KCNA3CCR1CCR3 | |
| SCHEMBL11599560 | 0.86 | KCNA3 (0.66) | KCNA3RAB9ANPSR1CCR1CCR3 | |
| SCHEMBL11626788 | 0.84 | KCNA3 (0.57) | KCNA3RAB9ANPSR1CCR1CCR3 | |
| SCHEMBL11616292 | 0.83 | KCNA3 (0.73) | KCNA3RAB9ANPSR1CCR1CCR3 | |
| SCHEMBL11618101 | 0.81 | KCNA3 (0.55) | KCNA3RAB9ANPSR1CCR1CCR3 | |
| SCHEMBL11600408 | 0.78 | CYP3A4 (0.55) | KCNA3RAB9ANPSR1CCR1CHRM3 | |
| Hydrochloric Acid SCHEMBL11627731 | 0.77 | CCR3 (0.62) | KCNA3RAB9ANPSR1CCR1CCR3 | |
| SCHEMBL11731812 | 0.74 | CCR1 (0.59) | KCNA3CCR1CCR3 | |
| SCHEMBL6475410 | 0.73 | DRD2 (0.55) | KCNA3RAB9ANPSR1OPRM1DRD2 | |
| SCHEMBL11601553 | 0.73 | KCNA3 (0.65) | KCNA3RAB9ANPSR1CCR1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE29556-E | 1,1-Diaryl-1-oxadiazol-alkylamines | G. D. SEARLE & CO. (US) | 1978-02-28 | — | — | US | disclosed |