SCHEMBL11599707

SCHEMBL11599707

Cc1cc(N)cc(C)c1O.Cc1ccc(N)c(C)c1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.42
TSHR P16473 5/20 0.42
CASP1 P29466 2/20 0.42
KDM4E B2RXH2 2/20 0.42
LMNA P02545 2/20 0.42
GAA P10253 2/20 0.42
MAPT P10636 2/20 0.42
PDE10A Q9Y233 1/20 0.42
PKM P14618 1/20 0.41
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
NPC1 O15118 1/20 0.37
MITF O75030 1/20 0.37
TP53 P04637 1/20 0.37
AGTR1 P30556 1/20 0.37
HTT P42858 1/20 0.37
RAB9A P51151 1/20 0.37
RPS6KA3 P51812 1/20 0.36
TDP1 Q9NUW8 4/20 0.35
CYP3A4 P08684 4/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29631738 0.87 ALDH1A1 (0.43) ALDH1A1TSHRCASP1KDM4ELMNA
SCHEMBL126200 0.87 ALDH1A1 (0.43) ALDH1A1TSHRCASP1KDM4ELMNA
SCHEMBL11326454 0.85 ALDH1A1 (0.42) ALDH1A1TSHRCASP1KDM4ELMNA
Hydrochloric Acid SCHEMBL29285342 0.85 ALDH1A1 (0.42) ALDH1A1TSHRCASP1KDM4ELMNA
Hydrochloric Acid SCHEMBL31026623 0.85 ALDH1A1 (0.42) ALDH1A1TSHRCASP1KDM4ELMNA
SCHEMBL655476 0.80 CA1 (0.58) ALDH1A1TSHRCASP1KDM4ELMNA
Hydrochloric Acid SCHEMBL8565881 0.78 CA1 (0.55) ALDH1A1TSHRCASP1KDM4ELMNA
SCHEMBL11388269 0.76 ALDH1A1 (0.56) ALDH1A1TSHRCASP1KDM4ELMNA
SCHEMBL6651758 0.75 ALDH1A1 (0.35) ALDH1A1TSHRCASP1KDM4ELMNA
Hydrochloric Acid SCHEMBL9690160 0.75 CA1 (0.52) ALDH1A1TSHRCASP1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4094861-A Process for the production of non-inflammable polytriazines BAYER AKTIENGESELLSCHAFT (DT) 1978-06-13 US disclosed